Background

Blood culture diagnostics is the gold standard diagnostic tool for the microbiological proof of sepsis. Knowledge of the causative pathogen and it’s susceptibility to anti-infectives allows for an adequate antimicrobial therapy and further diagnostic measures. This improves patient’s outcome, reduces lethality and lay-days.

The proof of clinical relevant bacteraemia or fungaemia in severe sepsis or septic shock works in about 30-40% of the cases under controlled study conditions. In Germany, the rate of microbiologically proven sepsis accounts for only ~ 10%. This indicates a significant shortfall in cause and methodology of the diagnostic course. Accordingly, only 16.5 blood culture sets were drawn per 1,000 patient days in Germany 2013/14, significantly lower than in other European countries (Antimicrobial resistance surveillance in Europe, http://www.ecdc.europa.eu).

The Thuringian hygiene order (ThürMedHygVO) 2012

According to § 23/4 of the amended Infection Protection Act (IfSG) 2011, an ongoing surveillance and assessment of nosocomial infections and pathogens with specific resistances has to be done with professional and acclaimed procedures. Data on the use of antibiotics has to be collected and sustainable cooperation by networking, especially with aim at agreement of standardized screening, management, and crossover criteria, has to be performed. In Thuringia, the respective order came into effect on 31st of July 2012